Whether airway hyperresponsiveness is a symptom of airway inflammation or airway remodeling, or whether it is the cause of long-term loss of lung function, remains controversial. Some investigators have hypothesized that aggressive treatment with anti-inflammatory therapies improves the long-term course of asthma beyond their salutary effects on parameters of asthma control and rates of exacerbation over time. 13 This contention has been supported by an observational study 14 that found long-term exposure to ICS was associated with an attenuation of the accelerated decline in lung function previously reported in asthmatics; more studies are required to substantiate these findings.
Feline leukemia virus can cause cancers of both the blood and lymphoid system in cats. The virus is occasionally transmitted from an infected queen to her kittens before birth but is more commonly acquired from close contact with infected cats, which shed the virus in saliva, urine and feces. If your cat is infected, he or she can pass the infection to other cats. The infection is not transmissible to people. Similarly feline immunodeficiency virus, which is similar to HIV in people, only affects cats and cannot infect people or other animals such as dogs.